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KMID : 0895420130230020041
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Journal of Korean Society of Occupational and Enviromental Hygiene
2013 Volume.23 No. 2 p.41 ~ p.49
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A Relationship between Serum Carcinoembryonic Antigen Concentrations and Job Titles of a Shipyard Workers
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Jung Kap-Yeol
Kim Jung-Won
Ye Byeong-Jin
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Abstract
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Objectives: The purpose of this study was to clarify the association between serum carcinoembryonic antigen (CEA) and type of work in the shipbuilding industry.
Methods: 1,072 final study subjects were admitted to a general hospital from April through July 2010 for the purpose of medical examination. Data on general characteristics such as age, smoking history, alcohol history and exercise habits was gathered through structured self-administered questionnaires. Information on job factors was collected from a medical examination, by interview and through company personnel data. Serum CEA levels were measured after eight hours’fasting and were analyzed by a radioimmunoassay.
Results: On univariate analysis, the mean serum CEA level was significantly higher among married (p=0.02), older age (p<0.01), longer work time (p<0.01), smokers (p<0.01), lower education (p<0.01), and indirect and direct exposure groups (p<0.01). On multiple regression analysis, serum CEA level was influenced by smoking (p=0.001), duration of work (p=0.019), and direct exposure group (p<0.001). However, among the direct exposure group, serum CEA level was not significantly different between welding, mounting, electro-device constructive work, grinding and cleaning, and painting.
Conclusions: The goal of this research was to determine if there were differences between serum CEA levels according to occupational role among shipyard workers. The direct exposure group of shipyard workers had a relatively higher level of serum CEA than did the indirect exposure group and office workers, most likely due to occupational exposure
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KEYWORD
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carcinoembryonic antigen, job title, shipyard worker
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